Oxford says vaccine has good immune response with two-dose regime

18 Dec
2020

Oxford says vaccine has good immune response with two-dose regime

By Staff Writer

Oxford says vaccine has good immune response with two-dose regime

LONDON: Oxford's Covid-19 vaccine candidate has a better immune response when a two full-dose regime is used alternately a full-dose followed by a half-dose booster, the university said on Thursday.

“The booster doses of the vaccine are both shown to induce stronger antibody responses than a single dose, the standard dose/standard dose convince the best response.”

The details from the Phase I/II clinical trials released on Thursday made no reference to the half-dose/full-dose regime which Oxford has said had been "unplanned" but approved by governor.

The university said it had toured two dosing regimes in early stage trials, a full-dose/full-dose regime and a full-dose/half-dose regime, investigated as a possible "dose sparing" strategy.

"The booster doses of the vaccine are twain shown to induce powerful antibody responses than a single dose, the standard dose/standard dose convince the best response," the university said in a statement.

The vaccine “stimulates big antibody and T cell functions,” it said after publishing further data from the Phase I/II clinical trials.

Note: - As every caution has been taken to provide our readers with most accurate information and honest analysis. Please check the pros and cons of the same before making any decision on the basis of the shared details.